Glucose (as glucose monohydrate) 20% (w/v)
Solution for infusion
A Clear, colourless solution, maybe not more than faintly yellow, no strange particles, packed in a colourless plastic bottle, sealed with plastic cap with two rubber discs inside.
Pharmacotherapeutic group: Solutions for parenteral nutrition, Carbohydrates
ATC code: B05BA03
Provides temporary relief from the symptoms of increased intracranial pressure and hypoglycemic coma.
The supplementation of energy in parenteral nutrition.
Hypersensitivity to the active substance and corn allergies (see sections special warnings and precautions for use and undesirable effects).
Clinically significant hyperglycemia.
The metabolism of glucose is an energy source for the body.
Glucose is a monosaccharide with six carbons, which is given by mouth or by intravenous infusion in the treatment of carbohydrate and fluid depletion. It is the preferred source of carbohydrate in parenteral nutrition regimens and is used in oral rehydration solutions for the prevention and treatment of dehydration due to acute diarrheal diseases. Glucose is also used in the treatment of hypoglycemia. Glucose is given orally in the glucose tolerance test as a diagnostic aid. Glucose solutions are also used as vehicles for other drugs. Solutions of glucose in water are iso-osmotic with blood at a concentration of anhydrous glucose 5.05% or glucose monohydrate 5.51%. Glucose solution 5% is therefore the strength often employed for fluid depletion; it may be given via a peripheral vein. Glucose solutions with a concentration greater than 5% are hyperosmotic and are generally used as a carbohydrate source; a 50% solution is often used in the treatment of severe hypoglycemia.
Glucose is rapidly metabolized into carbon dioxide and water.
Through oral route, glucose is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations of glucose occur about forty minutes after oral doses in hypoglycemic patients. It is metabolized via pyruvic or lactic acid to carbon dioxide and water with the release of energy.
Storage: In a cool and dry place at temperatures not exceeding 30oC, protect from light.
Shelf life: 3 years from manufacturing date.
Packing units:
12 plastic bottles of 500 mL per carton
24 plastic bottles of 250 mL per carton
