GLUCOSE 5% (as glucose monohydrate)

Glucose (as glucose monohydrate) 5% (w/v)

Solution for infusion

A Clear, colourless solution, no strange particles, packed in a colourless plastic bottle, sealed with plastic cap with two rubber discs inside.

Pharmacotherapeutic group: Other Intravenous Solution Additives

ATC code: B05BA03

INDICATIONS

Treatment of carbohydrate and fluid depletion.
Used as a vehicle and diluent for compatible medicinal products for parenteral administration.

CONTRAINDICATIONS

Glucose 5% solution is contraindicated in case of uncompensated diabetes, other known glucose intolerances (such as metabolic stress situations), hyperosmolar coma, hyperglycemia, hyperlactatemia.

Hypersensitivity to the active substance.

PHARMACODYNAMIC PROPERTIES

The pharmacodynamic properties of this solution are those of glucose, which forms the principal source of energy in cellular metabolism. Glucose 5% is given as a source of carbohydrate in parenteral nutrition. The Glucose 5% solution provides a caloric intake of 200 kcal/L. Furthermore, this glucose solution for infusion allows hydric supplementation without ionic supplementation.

Glucose 5% is an isosmotic solution, with an approximate osmolarity of 278 mOsm/L.

The pharmacodynamics of the additive will depend on the nature of the drug used.

PHARMACOKINETIC PROPERTIES

Glucose is metabolized via pyruvic or lactic acid to carbon dioxide and water with the release of energy.

The pharmacokinetics of the additive will depend on the nature of the drug used.

STORAGE, SHELF LIFE, PACKING UNITS

Storage: In a cool and dry place at temperatures not exceeding 30oC, protect from light.

Shelf life: 3 years from manufacturing date.

Packing units:

24 plastic bottles of 250 mL per carton

12 plastic bottles of 500 mL per carton

12 plastic bottles of 1000 mL per carton

GLUCOSE 5% (as glucose monohydrate)