NANOKINE

Each glass vial of 1 mL contains:

rHu EPO 2000 IU, 4000 IU, 10000 IU

Each prefilled syringe of 0.5 mL contains:

rHu EPO 2000 IU, 4000 IU

Each prefilled syringe of 1 mL contains:

rHu EPO 10000 IU

NANOKINE is produced from raw, high purity materials erythropoietin (EPO). The EPO is produced by recombinant DNA techniques on ovarian cell lines marsupial cheeks of China. The recombinant human erythropoietin and natural eryth ropoietin are shown to identically function in vivo. It stimu lates the production of red blood cells in bone marrow.

Pharmacotherapeutic group : Hematopoietic agents

INDICATION

Treatment of symptomatic anaemia associated with chronic renal failure (CRF) in adult and paediatric patients :

On haemodialysis and on peritoneal dialysis.
With renal insufficiency not yet undergoing dialysis.
On chemotherapy for solid tumours, malignant lymphoma or multiple myeloma, and at risk of transfusion as assessed by the patient's general status (e.g. cardiovascular status, pre-existing anaemia at the beginning stage of chemotherapy).
Increasing the yield of autologous blood from patients in a predonation programme.
Reducing exposure to allogeneic blood transfusions in adult non-iron deficient patients prior to major elective orthopaedic surgery, having a high perceived risk for transfusion complications.

CONTRAINDICATION

NANOKINE should NOT be used for patients :

Have uncontrolled hypertension.
Develop pure red cell aplasia (PRCA) following treatment with erythropoietin.
Hypersensitivity to the active substance or to any of the excipients.
Have surgery and cannot receive adequate antithrombotic prophylaxis for any reason.
Have autologous blood predonation programmes
Are scheduled for major elective orthopaedic surgery and not participating in an autologous blood predonation.
Suffer severe coronary, peripheral arterial, carotid artery disease or cerebral vascular disease, including patients with recent myocardial infarction or cerebral vascular accident.

STORAGE, SHELF LIFE, PACKING UNITS

Storage:

At 2^oC - 8^oC. Do not freeze. Protect from light.

Shelf life:

24 months from manufacturing date.

Packing units:

Box of 01 vial of solution for injection NANOKINE 2000 IU , 4000 IU , 10000 IU (1 mL)

Box of 01 prefilled syringe of solution for injection

NANOKINE 2000 IU (0.5 mL) , 4000 IU (0.5 mL), 10000 IU (1 mL)

NANOKINE

NANOKINE

NANOKINE

NANOKINE

NANOKINE

NANOKINE

NANOKINE

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